DMP Guide: MSCA for Pharmacology, Toxicology & Pharmacy

1. Funder Policy & Open Data Compliance

In alignment with international open-science mandates, Marie Skłodowska-Curie Actions requires all principal investigators to submit a comprehensive Data Management Plan (DMP) with their grant application. A robust DMP details how research data will be collected, processed, documented, stored, shared, and preserved both during and after the project.

For projects in the field of Pharmacology, Toxicology & Pharmacy, managing data correctly is essential not only for compliance, but also to support peer-review validation and reproducibility. All DMPs must be submitted through the Funding & Tenders Portal portal, using standard institutional guidelines.

2. Data Types, Formats, and Metadata Standards

A high-quality DMP must explicitly identify the types of data that will be generated and specify open, non-proprietary file formats to ensure long-term usability. For Pharmacology, Toxicology & Pharmacy, datasets typically range from raw observational measurements to curated computational models.

Biological data streams for **Pharmacology, Toxicology & Pharmacy** focus on cellular imaging and experimental protocols. The DMP specifies long-term archival plans, structured indexing mapped to the **Chemicals and Drugs** terminology, and secure patient anonymisation to satisfy **MSCA** auditors.

To guarantee discoverability, datasets should be documented using standardised metadata schemas that map to the Chemicals and Drugs branch of scholarly vocabularies. This ensures indexers and crawlers can crawl and identify research outputs accurately.

3. Step-by-Step DMP Construction Protocol

When preparing your DMP for a MSCA proposal, structure your document around these core sections:

1. Data Collection and Generation:
   Describe the methodology, instrumentation, or software used to collect or generate new data. Detail quality assurance and quality control measures implemented at your facility.
2. Documentation and Metadata:
   Explain how the data will be documented, including accompanying read-me files, data dictionaries, and laboratory notebooks. Specify the metadata standards to be utilized (using Dublin Core, ChEMBL schema, CDISC standard as standard).
3. Ethics, Intellectual Property, and Consent:
   Address how sensitive or confidential datasets will be handled. Detail anonymisation processes, access controls, and compliance with institutional ethics boards.
4. Storage, Backups, and Security:
   State where data will be stored during active research. Detail automated backup schedules, server redundancies, and access authorisation protocols.
5. Long-Term Preservation and Archiving:
   Select the digital repository for post-project archiving (such as PubChem, ClinicalTrials.gov, Zenodo, Dryad, and directory servers mapped in Embase, PubMed & TOXLINE). Confirm that the repository supports persistent identifiers (handles/DOIs) and provides secure preservation.

Open Science Workflows, Data Curation & Repositories

A compliant data management plan dmp for research projects in Pharmacology, Toxicology & Pharmacy must detail the specific data collection methods and the precise data curation standards that govern the project. By configuring customizable dmptool workflows, research teams can seamlessly align their files with Marie Skłodowska-Curie Actions's schemas. Our project methodology mandates systematic data cleaning and continuous verification of data integrity to support reproducible data wrangling pipelines. To aid secondary usage, a comprehensive data dictionary will accompany every published record. From a storage perspective, researchers must evaluate storing datasets in a highly indexed data warehouse versus a scalable data lake, analyzing the trade-offs of a data lake vs data warehouse architecture for downstream data analysis and exploratory data analysis inside the Funding & Tenders Portal workspace. Open-access guidelines require teams to push finalised files to the dryad data repository, configure shared figshare datasets, or initiate a zenodo data upload, securing a permanent slot in the data citation index that aligns with nsf data management plan directives. We will enforce structured data versioning protocols using the open science framework osf to streamline reproducible data sharing that is fully compliant with fair data principles examples. Additionally, all collaborative research must respect the care data principles and uphold indigenous data sovereignty care policies, keeping community interest central to the data lifecycle. Implementing this storage layout satisfies compliance protocols overseen by the MSCA data audit team.

4. Frequently Asked Questions