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SKU DIGI-FYRA-EODC
Digivac
FYRA for End of Primary Drying Detection | Vacuum Drying Monitoring | CE, UL, CSA
$3,611.88
In stockDigiVac FYRA configured for end-of-primary-drying detection, pairing a convection-enhanced Pirani (Lesker 275, KF25) against a Quantum DCP capacitive-piezo gauge so that the converging difference between their readings signals the end of primary drying in a freeze dryer or vacuum oven. Listed control range is 0.01 to 100 Torr with accuracy quoted over 0.0005 to 1000 Torr. CE, UL and CSA.
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Description
FYRA End of Primary Drying Detection for indicating that the end of primary drying has occurred in freeze dryers and vacuum ovens.
FYRA for End of Primary Drying Detection. This bundle is set-up to allow for vacuum drying applications like freeze-drying and vacuum ovens to help determine the end of drying. Will help you detect when most of the water or residual solvent from a product has been removed or the end of primary drying has been reached in a vacuum drying application.
Background on How this FYRA End of Primary Drying package works:
When a freeze dryer is equipped with both a thermal and direct measurement, these sensors can be utilized to indicate the end of primary drying (Source).
Step One: Clean process documentation | Get a baseline
Characterize the convection-enhance pirani and the capacitance manometer (in this case the DCP Quantum) against each other in a dry, empty and refrigerated system. The freeze dryer is turned on, as per the manufacturer’s operator manual, with nothing on the shelf. The shelf temperature can be left at room temperature, and if so the cold trap, the condenser, and the vacuum pump should be on and running for a period of time
The vacuum oven or freeze dryer is allowed a period of time to become stable in this condition and the pirani and capacitance manometers are read. The difference in their pressure readings in a dry, empty and refrigerated freeze dryer will be relatively small (mT to 10’s of mT) when the system is working properly.
DigiVac will NOT calibrate these two gauges against each other. There may always be slight differences in their readings do to their difference in design.
The difference in pressure (ΔP) between these two gauges, when dry, empty and refrigerated, indicates how close they come together when there is little to no water vapor in the gas mix over the product.
Step 2: Drying with Product
The intent of primary drying is to maximize the sublimation rate within the product. As such the gases in the chamber have a high water vapor content.
The pirani sensor will read a higher pressure than the capacitance manometer. As freeze drying progresses the amount of ice converting to vapor through the sublimation process will decrease as the product becomes lyophilized from top through the bottom of the product.
Eventually the pirani and capacitance manometers will approach the ΔP that was established in a dry, empty and refrigerated system. Approaching this ΔP value indicates that the end of primary drying has occurred.
The DigiVac FYRA controller has a rich remote command line interface which enables the user a high degree of remote control and monitoring from any computer when communicating through the USB port.
Calibrated—Every FYRA is calibrated and pretested under actual vacuum against a NIST standard (Need NIST traceable documentation? Add this option to your order)
Applications—Ideal for End of Drying Detection, Freeze Drying Primary Drying Monitoring, and Vacuum Oven Drying Monitoring and Detection
DCP Quantum DuoSense Measurement Range: .05 mT to 1000 Torr
275 Convection-enhanced pirani Measurement Range: 0.1mT to 1000 Torr
FYRA Bleed Vacuum Controller Components:
FYRA controller
Convection-enhance pirani KF25 gauge sensor | Lesker 275, driver card, and pirani sensor cable
Quantum DCP Gauge and driver card | DuoSENS Capacitive Piezo Vacuum Sensor 0.01 to 1000 Torr, Gas Independent
Optional: KF25 Manual Purge Valve | supports purging and flushing the system so that pressure delta is not affected by trapped vapors.
3 Simple Steps for Vacuum Process Set-up with FYRA Vacuum Controller:
Plumb the vacuum gauge(s) and valve into your vessel
Connect the sensor, power, and I/O cables into FRYA
Measure and control vacuum
Learn More Watch DigiVac’s Demonstration from CannaCon OKC 2022
Downloads
User Manual
Data Sheet
Quick Start
Technical Specifications
Units
Torr, mbar, kPa, Pa, microns (choose mTorr), millitorr (mTorr), mmHg, Hectopascal
Control Range
1×10-2 – 1×10+2 Torr
Range with Accuracy
5E-4 -1000 Torr
Sensor Type
536 KF25
Dimensions
1.7”H x 3.52”W x 5.35” Deep
Certifications
CE,UL,CSA
Frequently asked questions
What is in this bundle?+
A FYRA controller; a convection-enhanced Pirani KF25 gauge sensor (Lesker 275) with its driver card and sensor cable; and a Quantum DCP gauge with driver card - the DuoSENS capacitive-piezo sensor, 0.01 to 1000 Torr, gas independent. A KF25 manual purge valve is listed as an option, which supports purging and flushing so that trapped vapours do not distort the pressure difference between the two gauges.
How does end-of-primary-drying detection actually work?+
First you establish a baseline: run the freeze dryer dry, empty and refrigerated, and read both gauges. The difference between them will be small, from a few millitorr to tens of millitorr, in a healthy system. During primary drying the chamber gas has a high water-vapour content, so the Pirani reads higher than the capacitance manometer. As sublimation slows and the product lyophilises through, the two readings converge back toward the baseline difference - and approaching that value indicates primary drying has ended. DigiVac does not calibrate the two gauges against each other; small design-related differences in their readings are expected and are the point of the method.
What measurement and control ranges apply?+
The listing gives a control range of 0.01 to 100 Torr and a range with accuracy of 0.0005 to 1000 Torr for the assembled bundle. Note that the two sensors have different ranges: DigiVac's own datasheet specifies the Quantum DCP DuoSENS at 0.01 to 1000 Torr, plus/minus 3%, while the 275 convection-enhanced Pirani is listed at 0.1 millitorr to 1000 Torr and is what extends the low end. The listing's own sensor-range table quotes a lower figure for the DCP than DigiVac's datasheet does; where the two disagree, use the datasheet.
What units and what physical size?+
Selectable units are Torr, mbar, kPa, Pa, microns, millitorr, mmHg and hectopascal. The listing gives controller dimensions of 1.7 in high x 3.52 in wide x 5.35 in deep, and a sensor type of 536 KF25.
Can it be controlled or monitored remotely?+
Yes. The FYRA controller has a command-line interface over its USB port, which gives remote control and monitoring from any connected computer.
What calibration and certification does it carry?+
DigiVac states that every FYRA is calibrated and pretested under actual vacuum against a NIST standard. Listed certifications are CE, UL and CSA. Setting up is described as three steps: plumb the gauges and valve into the vessel, connect the sensor, power and I/O cables to the FYRA, then measure and control.
Related products
FYRA Vacuum Regulator | 10 millitorr to 6 Torr | 2 Sensors for Roughing Pump + System, UL, CSA,CE
DigiVac FYRA configured as a two-sensor vacuum regulator, listed for 10 millitorr to 6 Torr with sensors for both the roughing pump and the system. Control is by upper and lower set points driving a 24 VDC valve directly, with a 3.9 in touchscreen, USB and 0-10 V analogue in and out. WiFi is a selectable option. 100-240 VAC 50/60 Hz; UL, CE and CSA.
