Shipping a live animal by air — a rodent colony transferred between a breeding vendor and a research institution, a fish or amphibian model shipped between labs, or a research-use animal moving through a contract facility — falls under a different rulebook than shipping chemicals or biological samples. The IATA Live Animal Regulations (LAR) is the International Air Transport Association’s manual governing how live animals must be contained, documented, labeled, and handled to be accepted for air transport. This guide explains what the LAR covers, how it differs from the IATA Dangerous Goods Regulations (DGR) and from wildlife/agriculture import-permit requirements, and what a lab or procurement office needs to have in place before a live-animal shipment can move.
What the IATA Live Animal Regulations Are
The IATA Live Animal Regulations is IATA’s annually updated manual specifying the minimum standards for transporting live animals by air — container construction, ventilation, labeling, documentation, and handling. It is the reference airlines, freight forwarders, and ground handlers use to decide whether a live-animal shipment is acceptable, in the same way the IATA Dangerous Goods Regulations (DGR) governs hazardous cargo. The LAR incorporates requirements drawn from CITES (the Convention on International Trade in Endangered Species of Wild Fauna and Flora) for listed species, from national wildlife, agriculture, and public-health import/export rules, and from individual airlines’ own operating variations — a shipment that meets the LAR’s baseline can still be refused by a specific carrier that applies additional restrictions.
For research organizations, the LAR applies whenever a live animal used in or destined for research — rodents, fish, amphibians, avian species, or larger animals — is offered for air transport, whether that shipment is a commercial purchase from a breeding vendor, a transfer between collaborating institutions, or a return shipment to a supplier. It applies regardless of whether the animal is itself a CITES-listed or otherwise regulated species; unregulated laboratory strains (standard mouse and rat strains, for example) still have to be packed, labeled, and documented to LAR container and handling standards to be accepted by a carrier.
How the LAR Differs From the IATA DGR and From Import Permits
Labs that already ship chemicals, biological substances, or dry ice by air are usually familiar with the IATA Dangerous Goods Regulations — a related but separate IATA manual covering hazard classification, packing instructions, and Shipper’s Declarations for dangerous goods. Live animals are not dangerous goods and are not classified against the DGR’s nine hazard classes; they have their own dedicated manual with its own container standards, documentation, and training track. The two regimes can apply to the same shipment at once, though: a live specimen packed with dry ice as a cold source, or shipped alongside a battery-powered environmental monitor, can trigger both the LAR (for the animal) and the DGR (for the dry ice or battery) simultaneously, each with its own packing and paperwork requirements.
The LAR is also distinct from the import/export permit programs that separately govern moving live animals across a border — in the US, USDA APHIS Veterinary Services import permits and, for certain species and pathogens, CDC import permits. Those permits authorize the animal’s entry into or exit from a country under agriculture and public-health law; the LAR governs how the animal is physically packaged and handled by the carrier once a shipment is authorized to move. A shipment can be fully permit-compliant and still be refused by an airline for failing an LAR container or documentation requirement, and vice versa — the two compliance tracks run in parallel and both have to be satisfied. See CASRAI’s guides on USDA APHIS Import Permits and the CDC Import Permit Program for the permitting side of moving research animals or animal-derived material across a border.
Container Requirements
The core of the LAR is its set of numbered Container Requirements (CRs), each specifying the minimum construction standard — material, strength, ventilation openings, spacing bars, floor and door design — for a particular species or group of species. A container built to the wrong CR, or one that is structurally sound but undersized for the animal(s) inside, is grounds for a carrier to refuse the shipment outright. Because the applicable CR depends on species (and, for some species, size, age, or group size), procurement and shipping staff need to confirm the correct CR for the specific animal being shipped rather than reusing a container design from a previous shipment of a different species. Most institutional vendors and specialist live-animal freight forwarders maintain LAR-compliant containers as standard stock for common laboratory species, which is one practical reason labs frequently route live-animal shipments through a specialist carrier or forwarder rather than general cargo channels.
Documentation and Labeling
A compliant LAR shipment requires several pieces of documentation and marking, in addition to any wildlife/import permits the shipment separately needs:
- Shipper’s Certification for Live Animals — a signed attestation, in the LAR’s standard format, that the animal was healthy and fit to travel at the time of shipment, was fed and watered within the LAR’s specified window before dispatch, and is packed in a container that meets the applicable Container Requirement.
- Feeding and watering instructions — attached to the outside of the container so ground handlers and, if needed, the carrier can care for the animal during a delay or layover.
- “Live Animals” labeling and orientation marking — the container must carry the LAR’s live-animal label along with correct orientation (“This Way Up”) marking.
- Any species-specific health certificates or CITES/wildlife permits the origin, transit, and destination jurisdictions require, which travel with the shipment alongside the LAR paperwork but are issued under separate authority (a national veterinary/agriculture agency or CITES management authority, not IATA).
An incomplete or inconsistent set of these documents is one of the most common reasons a carrier holds or refuses a live-animal shipment, independent of whether the container itself is compliant.
Carrier Acceptance, Embargoes, and Species Restrictions
Airlines are not obligated to carry live animals, and individual carriers layer their own acceptance policies on top of the LAR baseline — some decline categories of live-animal cargo entirely, others apply seasonal temperature embargoes (refusing live-animal cargo during extreme heat or cold on a given route, for animal-welfare reasons), and route or connection availability for live-animal shipments is often more limited than for general cargo. Over the past several years, a number of commercial passenger carriers have also restricted or stopped accepting non-human primates shipped for research use specifically, a shift driven by public and shareholder pressure rather than an LAR or regulatory change — labs and procurement offices sourcing non-human primates should confirm current carrier acceptance policy directly with the vendor or freight forwarder rather than assuming any given route or carrier is available, since this landscape has changed faster than general LAR container/documentation requirements have. Building in lead time to confirm carrier acceptance, and working with a forwarder experienced in live laboratory-animal shipments, materially reduces the risk of a shipment being booked and then refused at the point of tender.
Training Requirements
Like the DGR, the LAR requires that personnel who prepare, pack, label, and document live-animal shipments have received function-specific training in the current LAR requirements, renewed on a periodic cycle. This applies to lab or vivarium staff who personally pack and certify a shipment, not only to a shipping department’s staff; a lab that packs its own live-animal shipments (rather than routing every shipment through a trained third-party forwarder) needs its own trained staff to complete the Shipper’s Certification. Institutions that ship live research animals only occasionally more commonly route shipments entirely through a specialist live-animal freight forwarder or the vendor’s own logistics service specifically to avoid maintaining in-house LAR-trained staff for infrequent shipments.
Why This Matters for Research Procurement
For a lab, vivarium, or procurement office, the practical takeaway is that “the vendor will handle shipping” is not automatically true for live-animal orders the way it often is for reagents or supplies. Confirming who is responsible for LAR compliance — the vendor, a freight forwarder, or lab/institutional staff — before a live-animal order is placed avoids a shipment being delayed or refused because no party had current LAR training, the wrong container was used, or a document was missing. This sits alongside, not instead of, the underlying import/export permitting for the species and route in question; a fully LAR-compliant shipment still cannot move without whatever USDA APHIS, CDC, CITES, or destination-country permits the specific animal and route require.
Frequently Asked Questions
Do standard laboratory mouse and rat strains fall under the IATA Live Animal Regulations?
Yes. The LAR applies to any live animal offered for air transport, not only CITES-listed or wildlife species. A shipment of standard laboratory rodents still has to use an LAR-compliant container, carry the required labeling, and be accompanied by a completed Shipper’s Certification for Live Animals.
Is the IATA LAR the same as the IATA Dangerous Goods Regulations?
No. They are separate IATA manuals. The DGR governs hazardous cargo classified into nine UN hazard classes; live animals are not dangerous goods and are governed instead by the LAR’s own container, documentation, and training requirements. A single shipment can be subject to both if it combines a live animal with a dangerous good, such as dry ice used as a coolant.
Does LAR compliance replace the need for an import permit?
No. The LAR governs how a carrier will accept and handle the physical shipment; it does not authorize crossing a border. Import or export of the animal itself is separately governed by the destination and origin countries’ wildlife, agriculture, or public-health authorities — in the US, this typically means USDA APHIS and, for certain species or pathogens, CDC import permits — and both the LAR and the applicable permits have to be satisfied for the shipment to move.
Who has to be trained on the LAR at a research institution?
Anyone who personally packs, labels, or certifies a live-animal shipment needs current, function-specific LAR training, whether that person works in a shipping department or a vivarium. Institutions that route all live-animal shipments through a trained third-party forwarder or the vendor’s own logistics service can rely on that party’s training instead of maintaining their own.
Can an airline refuse to carry a research animal even if the shipment is fully LAR-compliant?
Yes. Airlines set their own live-animal acceptance policies on top of the LAR baseline, including species restrictions, seasonal temperature embargoes, and route-specific limits. Non-human primate shipments for research use in particular have become harder to route commercially as more passenger carriers have restricted or stopped accepting them, independent of LAR compliance.







