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Program of Veterinary Care (PVC)

A Program of Veterinary Care (PVC) is the documented set of policies, procedures, and staffing arrangements through which an institution's Attending Veterinarian provides adequate veterinary care to animals used in research, teaching, and testing. It is a required component of an animal-care-and-use program under Animal Welfare Act regulations (9 CFR 2.33) and, in parallel, under PHS Policy for PHS-supported vertebrate-animal research. A program qualifies as an adequate PVC only if it addresses, at minimum: preventive medicine (quarantine, disease surveillance, herd/colony health monitoring, vaccination and parasite control where applicable); appropriate methods for preventing, controlling, diagnosing, and treating disease and injury; guidance and oversight of surgery (pre-, intra-, and post-operative care) and of anesthesia and analgesia use, including a mechanism for the Attending Veterinarian to require or adjust pain relief; a means of communication so personnel promptly report animal health concerns; and 24-hour availability of emergency veterinary care. Where the Attending Veterinarian serves in a part-time or consultant capacity rather than full-time employment, 9 CFR 2.33 requires the arrangement to be formalized through a written program of veterinary care and regularly scheduled site visits, not an informal or on-call-only relationship.

ByCASRAI Editorial Board
· Last updated 23 Jul 2026

Examples

Worked examples

  • Is an instance

    A university's IACUC-approved animal care and use program includes a written PVC specifying that the part-time consulting Attending Veterinarian visits each animal facility on a fixed biweekly schedule, reviews colony health records at each visit, and has standing authority to order treatment, adjust an approved anesthesia/analgesia plan, or euthanize an animal without waiting for investigator sign-off when welfare requires it.

  • Is an instance

    A PVC document sets out the institution's after-hours emergency contact chain (on-call veterinary technician, backup Attending Veterinarian, nearest emergency veterinary facility) so that a sick or injured animal discovered outside normal business hours still receives care within the 24-hour-availability standard, and the document is reviewed and updated at the IACUC's semiannual program review.

Counter-examples

Looks similar, but isn't

  • Not an instance

    An institution that lets individual investigators arrange ad hoc veterinary consults only when they personally judge one necessary, with no institution-wide written procedures, no defined surgical/anesthesia oversight role for a veterinarian, and no after-hours emergency coverage, does not have a Program of Veterinary Care in the regulatory sense -- even if a veterinarian is occasionally involved -- because the AWA/PHS Policy requirement is for a documented, institution-level program with defined veterinary authority, not case-by-case access to veterinary advice.

Editorial commentary

The Program of Veterinary Care (PVC) is one of the mandatory components of an institution’s animal care and use program, required alongside the IACUC itself under both the Animal Welfare Act (AWA) and PHS Policy. Where the IACUC provides oversight and protocol approval, the PVC is the operational mechanism through which day-to-day and emergency veterinary medical care is actually delivered, under the direction of the institution’s Attending Veterinarian (AV).

Regulatory basis

For AWA-covered species, 9 CFR 2.33 (Subpart D, ‘Attending veterinarian and adequate veterinary care’) requires every registered research facility to employ an Attending Veterinarian, under a full-time, part-time, or consultant arrangement, with delegated authority to ensure adequate veterinary care. When that arrangement is part-time or consultant-based — common at smaller institutions — the regulation specifically requires a written program of veterinary care plus regularly scheduled visits to the facility, rather than an informal on-call relationship. PHS Policy imposes a parallel requirement for PHS-supported vertebrate-animal research, reaching species the AWA’s own statutory definition excludes (purpose-bred rats, mice, and birds). Because of this coverage gap, most PHS-funded institutions apply a single institution-wide PVC covering all vertebrate species regardless of which regulation technically applies to a given species, an approach consistent with adopting the Guide for the Care and Use of Laboratory Animals as unified institutional policy.

What an adequate PVC must cover

  • Preventive medicine — quarantine and acclimation of newly arrived animals, disease surveillance, colony/herd health monitoring, and species-appropriate vaccination or parasite-control protocols.
  • Diagnosis and treatment of disease and injury — documented procedures for recognizing, diagnosing, and treating illness or injury, including guidelines for when a veterinarian must be consulted or must intervene directly.
  • Surgery, anesthesia, and analgesia oversight — veterinary guidance covering pre-operative, intra-operative, and post-operative care, and a defined mechanism for the Attending Veterinarian to review, require, or adjust anesthetic and analgesic use in approved protocols.
  • Emergency care — 24-hour availability of veterinary care or an equivalent emergency-response pathway, so that an animal in distress outside normal working hours is not left without access to treatment.
  • Reporting and communication channels — a defined route for animal care staff and investigators to promptly report health concerns to veterinary staff.

How the PVC relates to Attending Veterinarian authority

The PVC is the documented program; the Attending Veterinarian is the individual with institutional authority to carry it out. Under 9 CFR 2.33, the AV must hold direct or delegated authority to intervene — ordering treatment or euthanasia, requiring appropriate anesthesia or analgesia, or suspending a procedure causing unrelieved pain or distress — independently of, and in addition to, the IACUC’s own separate suspension authority under 9 CFR 2.31 and PHS Policy IV.C.6. The AV is also required to be a voting member of the IACUC, which reviews the adequacy of the PVC as part of its semiannual program review and facility inspection.

PVC and accreditation

A documented, functioning PVC is also an expectation reviewed during AAALAC International site visits, since AAALAC’s accreditation standards incorporate the Guide for the Care and Use of Laboratory Animals, which itself treats an adequate veterinary care program as a core element of institutional animal-care-and-use programs. An institution can satisfy the letter of AWA/PHS Policy without AAALAC accreditation, since accreditation is voluntary, but AAALAC reviewers will still evaluate whether the PVC in place is functioning in practice, not just documented on paper.

Related concepts

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