Written and maintained by CASRAI Editorial Board
Last updated
Environmental health is the field that studies how the physical, chemical, and biological factors in a person’s surroundings — the air they breathe, the water they drink, the food supply, the housing and neighborhoods they live in, and the wider climate — affect human health, and how to prevent the harm. It sits inside public health but draws heavily on toxicology, epidemiology, chemistry, and engineering. This guide explains what the field covers, how its main subfields (exposure science, environmental epidemiology, toxicology, and risk assessment) fit together, how it differs from occupational health, who funds the research, and how people train for it — including the research-administration layer that general encyclopedia entries leave out.
Definition and scope
A widely used definition describes environmental health as the science that addresses all the physical, chemical, and biological factors external to a person, and all the related factors affecting behaviors. It covers the assessment and control of those environmental factors that can potentially affect health, and it is aimed at preventing disease and creating health-supportive environments. The emphasis on prevention is what separates it from clinical medicine: the unit of intervention is usually the environment itself (a contaminated well, a ventilation system, a regulatory limit), not an individual patient.
In practice the field spans a broad set of topics:
- Air quality — outdoor particulate matter and ozone, indoor air, combustion products, and the respiratory and cardiovascular outcomes studied in fields such as pulmonology.
- Water, sanitation, and food safety — drinking-water contaminants, wastewater, and foodborne hazards.
- Chemical exposures — metals, pesticides, solvents, industrial by-products, and consumer-product chemicals, including persistent compounds that accumulate in the body.
- Hazardous waste and contaminated sites — the health consequences of waste dumps and the cleanup of contaminated land.
- The built environment and housing — lead paint, mold, pests, noise, and neighborhood design.
- Climate and health — heat, extreme weather, wildfire smoke, and changes in the distribution of vector-borne disease.
- Environmental justice — the question of why some communities carry a disproportionate share of exposure.
Different organizations use slightly different names for overlapping territory: “environmental health,” “environmental health sciences” (the term used in the name of the U.S. National Institute of Environmental Health Sciences), and “environmental public health.” “Environmental health sciences” usually signals the research side — the laboratory, exposure, and population science — while “environmental health” alone often also covers the applied practice of inspection, regulation, and program delivery carried out by health departments.
The core subfields
Exposure science
Exposure science asks the question every other subfield depends on: who is actually exposed to what, how much, by which route, and when? A chemical in the environment harms no one until it contacts a person, so measuring or modelling that contact is a discipline in its own right. Exposure scientists work with several kinds of evidence:
- Environmental measurement — sampling air, water, soil, dust, and food, using fixed monitors or personal samplers worn by participants.
- Exposure modelling — estimating exposure from sources, geography, and behavior, for example with land-use regression or satellite-derived pollution surfaces, when direct measurement is not possible for everyone in a study.
- Biomonitoring — measuring a chemical or its metabolite in blood, urine, or other tissue, which captures the dose that actually entered the body from all routes combined.
- The exposome — a concept proposed by cancer epidemiologist Christopher Wild in 2005 to describe the totality of a person’s environmental exposures across the life course, as a counterpart to the genome. It has become a framing for large-scale, high-throughput measurement efforts.
The field’s professional home is the International Society of Exposure Science, and a leading journal is the Journal of Exposure Science & Environmental Epidemiology.
Environmental epidemiology
Environmental epidemiology studies the distribution and determinants of disease in populations in relation to environmental exposures. It borrows the standard designs described in What Is Epidemiology? — cohort studies, case-control studies, cross-sectional surveys, and time-series analyses — and applies them to exposures that are usually continuous, low-dose, long-term, and hard to measure. See case-control vs. cohort studies for how those designs trade off.
Several analytic problems recur in this work:
- Exposure misclassification — because exposure is rarely measured perfectly, effect estimates can be biased, usually toward the null when the error is non-differential.
- Confounding and effect modification — neighborhoods with more pollution often differ in income, housing, and access to care, so separating the pollutant’s effect from these correlates is central. See effect modification vs. confounding.
- Latency — diseases such as cancer can appear decades after the relevant exposure, so exposure history has to be reconstructed.
- Mixtures — people are exposed to many chemicals at once, and most statistical methods were built for one exposure at a time.
Results are commonly reported as a relative risk or odds ratio per unit increase in exposure (see odds ratio vs. risk ratio). When evidence from many studies of an exposure is pooled, reviewers need tools suited to observational data, such as ROBINS-E for risk of bias in studies of exposures and dose-response meta-analysis for modelling a trend across exposure levels.
Environmental toxicology
Toxicology supplies the mechanistic and dose-response evidence: experiments in cells, tissues, and animals that show how a substance is absorbed, distributed, metabolized, and excreted, what damage it causes, and at what dose. The sibling guide What Is Toxicology? covers the discipline in depth, and two related CASRAI pages show how toxicological dose concepts are used in practice: toxicokinetics in nonclinical safety studies and NOAEL and first-in-human dosing. Environmental health toxicology differs from drug toxicology mainly in the exposure scenario: low-level, chronic, often multi-route exposure of the general population, including sensitive groups such as infants, pregnant people, and older adults.
Risk assessment
Risk assessment is the structured process that turns the evidence above into a decision-ready estimate of risk. The standard framework comes from the U.S. National Research Council’s 1983 report Risk Assessment in the Federal Government: Managing the Process, widely called the “Red Book.” It divides risk assessment into four steps:
- Hazard identification — is the agent causally linked to a particular health outcome?
- Dose-response assessment — how does the probability or severity of the effect change with the magnitude of exposure?
- Exposure assessment — how much exposure occurs in the population of interest, through which routes?
- Risk characterization — a description of the nature and magnitude of the risk, including the uncertainty attached to it.
The EPA’s human health risk assessment practice follows this paradigm. The framework also separates risk assessment (the scientific estimate) from risk management (the decision about what to do, which weighs law, cost, feasibility, and values). Much of the controversy in environmental health policy lives in the gap between the two, and in the default assumptions used when data are sparse — for example, how to extrapolate from animal data to people, or from high doses to low ones. Exposure limits that come out of such processes, and the different bodies that publish them, are compared in PELs vs. TLVs vs. RELs.
Environmental health vs. occupational health
The two fields share methods and overlap in subject matter (a solvent can be both a workplace and a community exposure), but they differ in whose exposure they address and who has legal authority over it.
- Population and setting. Occupational health protects workers in the workplace — identifying, evaluating, and controlling hazards that cause injuries, illnesses, and fatalities at work. Environmental health addresses exposures in the general environment, shared by whole communities, including children, older adults, and people who never work with the hazard.
- Exposure levels. Workplace exposures are often higher than community exposures but occur in a population that is, on average, healthier than the general public (the “healthy worker effect”). Community exposures are usually lower but continuous, and they reach vulnerable groups.
- Regulators and research agencies. The Occupational Safety and Health Act, signed December 29, 1970, created both the Occupational Safety and Health Administration (OSHA), a Department of Labor agency that sets and enforces workplace standards, and the National Institute for Occupational Safety and Health (NIOSH), a research agency now part of the Centers for Disease Control and Prevention. Community environmental exposures are regulated mainly by the EPA and by state and local agencies.
- Professions. Industrial hygienists, occupational physicians, and safety professionals dominate the workplace side; environmental health specialists, sanitarians, and environmental epidemiologists work on the community side, with considerable crossover.
The research laboratory sits at the boundary. Labs are workplaces governed by occupational rules, yet their waste and releases fall under environmental law. See CASRAI’s guides on EPCRA Tier II reporting for research laboratories and CERCLA reportable quantities and spill reporting.
Who does what: the institutional landscape
NIEHS and the National Institutes of Health
The National Institute of Environmental Health Sciences (NIEHS) is the NIH institute dedicated to this field. It was established in January 1969, elevated from a division of environmental health sciences announced in 1966, and its mission is distinctive because it centers on prevention rather than treatment. Its work includes the journal Environmental Health Perspectives, first published in April 1972, and the Superfund Research Program, established in 1987 as an academically based, multidisciplinary program addressing the health and environmental problems of hazardous waste sites. NIEHS also helps lead the National Toxicology Program, an interagency partnership that includes the FDA’s National Center for Toxicological Research and CDC’s NIOSH. Environmental health research is also funded by other NIH institutes whose disease focus intersects with exposure, such as those studying cancer, lung and heart disease, and child health.
The EPA
The U.S. Environmental Protection Agency, created in 1970, is primarily a regulatory agency, but it also runs an intramural research enterprise and an extramural grant program. Its role in this field is distinct from NIEHS: EPA assesses risks and writes and enforces rules under statutes covering air, water, chemicals, and waste, and its risk assessments feed regulatory limits. The two agencies are complementary — NIEHS generates much of the basic and population science, EPA applies it in regulatory decisions — though the exact programs and priorities of each change over time and should be checked against current funding announcements.
Other U.S. agencies
CDC supports surveillance, biomonitoring, and environmental public health tracking; NIOSH carries out occupational research; the Agency for Toxic Substances and Disease Registry evaluates health effects at specific contaminated sites; and the FDA and USDA address food and product safety. State and local health departments carry out most front-line environmental health practice.
Outside the U.S.
Internationally, the World Health Organization develops air-quality and drinking-water guidelines, and national research councils fund the field alongside broader biomedical and environmental science programs — for example, see CASRAI’s overview of NERC funding for UK environmental science.
Funding environmental health research
For a U.S. investigator, the most common mechanism is the NIH R01 research project grant, with the many other mechanisms catalogued in NIH activity codes. Applications are submitted and tracked through eRA Commons, and funded awards carry data-sharing obligations described in the NIH Data Management and Sharing Plan guide. Applicants should understand the different roles of NIH staff (see Program Officer vs. Scientific Review Officer vs. Grants Management Specialist) and should check current funding-level information such as NIH paylines by institute before choosing which institute to target. Center- and program-based awards, such as Superfund-style research programs and environmental health centers, are managed differently from single-investigator grants, with additional administrative cores, multi-project budgets, and community engagement components.
Environmental health research raises recurring administration issues that a research office should anticipate:
- Human-subjects protections for studies that collect biospecimens and location data, which can be re-identifying even without names.
- Community and tribal partnerships, where data ownership and return of individual results to participants need agreement in advance.
- Long-term cohorts and biobanks, which require sustained budgets, specimen governance, and data-sharing plans.
- Field work and laboratory analysis costs, including sampling campaigns, analytical chemistry cores, and instrument time.
- Subawards to community organizations, health departments, and partner universities.
Methods and tools
- Analytical chemistry — mass spectrometry and related methods for detecting trace contaminants in environmental and biological samples.
- Geospatial analysis — geographic information systems, remote sensing, and spatial statistics to assign and map exposure.
- Statistical methods — multilevel and time-series models, exposure-response curves, causal-inference approaches, and mixtures methods, with rates typically expressed per person-time at risk.
- Experimental toxicology — in vitro assays, animal studies, and increasingly computational and high-throughput screening approaches.
- Systematic review — structured evidence synthesis adapted to environmental exposures, since randomized trials of harmful exposures are not ethical.
A brief history
Modern environmental health grew out of 19th-century sanitary reform — clean water, sewage, and housing as responses to epidemic disease — and later expanded to chemical hazards. In the United States, institutional milestones cluster around 1969–1972: NIEHS became an institute in 1969, the Occupational Safety and Health Act and the EPA arrived in 1970, and Environmental Health Perspectives began publishing in 1972. The 1983 NRC risk assessment framework gave the field its common vocabulary, and programs such as the Superfund Research Program (1987) tied academic research to contaminated-site problems. More recent shifts include the exposome concept, a stronger focus on environmental justice, and growing attention to climate-related health effects.
Training and career paths
People enter the field through several routes:
- Public health degrees — the MPH or MS with a concentration in environmental health, and the PhD or ScD in environmental health sciences, offered in schools of public health (accreditation of these schools and programs is handled by the Council on Education for Public Health). Concentrations typically combine exposure science, toxicology, epidemiology, and biostatistics.
- Undergraduate environmental health programs, which prepare graduates for practice in health departments, and credentials such as the Registered Environmental Health Specialist/Registered Sanitarian offered through the National Environmental Health Association.
- Industrial hygiene — a related path toward workplace exposure assessment, with certification through the American Board of Industrial Hygiene.
- Adjacent sciences — chemistry, atmospheric science, and civil or environmental engineering degrees, followed by postdoctoral work in exposure or health.
Careers include academic research, government (EPA, CDC, NIEHS, state and local health departments), consulting, industry compliance and product safety, non-profit advocacy, and community-based work. Specific salaries and hiring trends change quickly and are best checked against current labor statistics.
Societies and journals
- Journals: Environmental Health Perspectives (published through NIEHS) and the Journal of Exposure Science & Environmental Epidemiology; many papers also appear in general epidemiology and toxicology journals.
- Societies: the International Society of Exposure Science, the International Society for Environmental Epidemiology, the Society of Toxicology, the Society of Environmental Toxicology and Chemistry, the National Environmental Health Association, and the American Industrial Hygiene Association on the workplace side.
Frequently asked questions
What is environmental health in simple terms?
It is the study and control of environmental factors — air, water, food, chemicals, housing, and climate — that can affect human health, with the goal of preventing disease rather than treating it after it appears.
What is the difference between environmental health and environmental science?
Environmental science studies the natural environment and how it changes. Environmental health asks specifically how environmental conditions and exposures affect human health, so it requires health outcome data and methods from epidemiology and toxicology in addition to environmental measurement.
What is exposure science?
Exposure science is the study of contact between people (or ecosystems) and chemical, physical, or biological agents: how much, by which route, and over what time. It provides the exposure estimates that environmental epidemiology and risk assessment depend on.
What does NIEHS fund?
NIEHS funds research on how environmental exposures influence human health and disease, including laboratory, population, and translational studies, and runs programs such as the Superfund Research Program. Check current NIEHS funding announcements for the active priorities and mechanisms rather than relying on a general description.
What is the difference between environmental health and occupational health?
Occupational health concerns hazards in the workplace and the protection of workers, regulated mainly through OSHA with research by NIOSH. Environmental health concerns exposures in the general environment shared by communities, regulated mainly through the EPA and state and local agencies. The two overlap whenever the same agent affects workers and neighbors.
What are the four steps of risk assessment?
Hazard identification asks whether an agent can cause harm; dose-response assessment asks how harm varies with dose; exposure assessment estimates who is exposed and how much; and risk characterization combines these into an estimate of risk with its uncertainties.
What degree do you need to work in environmental health?
Entry-level practice roles often require a bachelor’s degree in environmental health or a related science, sometimes with a credential. Research and leadership roles typically require an MPH or MS, and independent research careers usually require a doctorate in environmental health sciences, epidemiology, toxicology, or a related field.
Related CASRAI resources
Environmental health connects to several other disciplines in CASRAI’s branches-of-science series. See the full index at Branches of Science, and the related guides on public health, epidemiology, toxicology, and health services research.








