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Organic Process Research & Development (OPRD)

Organic Process Research & Development (OPRD) is a peer-reviewed journal published by the American Chemical Society (ISSN 1083-6160) focusing on the scale-up, safety, and chemical manufacturing of fine organics and pharmaceuticals. Its citation performance is tracked through journal-level citation ratios, including OpenAlex's 2-year mean citedness (3.91) and Clarivate's proprietary Journal Impact Factor in the Journal Citation Reports (JCR). Per DORA and CoARA principles, journal-level citation metrics describe publication-wide citation volume and must not be used as a proxy for the scientific merit of individual articles.

ByCASRAI Editorial Board
· Last updated 8 Nov 2026
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Examples

Worked examples

  • Is an instance

    A process chemist evaluating Organic Process Research & Development (OPRD) for submitting a pilot-plant scale-up paper, noting its focus on chemical manufacturing and process safety alongside citation metrics.

  • Is an instance

    A research administrator reviewing OPRD's journal-level metrics (such as OpenAlex 2-year citedness and Clarivate JCR indexing) while adhering to DORA principles by assessing the specific article rather than the journal average.

Editorial commentary

Quick answer: Organic Process Research & Development (OPRD) is a peer-reviewed journal published by the American Chemical Society (ACS) (ISSN 1083-6160, e-ISSN 1520-586X). Founded in 1997, OPRD focuses on the transition of chemical reactions from laboratory discovery to commercial manufacture, including pilot-plant scale-up and process safety. In open scholarly databases, OpenAlex records a 2-year mean citedness of 3.91, an h-index of 144, and over 7,100 cataloged works. Proprietary ratios, like Clarivate’s Journal Impact Factor in Journal Citation Reports (JCR), are updated each June; verify current proprietary numbers directly in JCR.

Organic Process Research & Development (abbreviated as OPRD) serves as a primary venue for researchers working in chemical engineering and specialty chemical manufacturing. While conventional synthesis journals emphasize novel molecular targets at milligram scale, OPRD focuses on scalable process chemistry: reaction optimization, reactor design, continuous flow, solvent replacement, heat transfer, and hazardous waste minimization.

Citation Metrics and Calculation Method

Journal-level citation metrics evaluate aggregate citation frequency. The foundational two-year citation metric calculates the ratio of citations received in a calendar year to citable items published during the preceding two years:

Metric Ratio = (Citations in Year Y to items published in Y-1 and Y-2) / (Total citable items published in Y-1 and Y-2)

Because official Clarivate JCR data sits behind a commercial paywall, open tracking systems provide complementary verified data. According to OpenAlex (entity S107255770), OPRD has accumulated 165,394 citations across 7,102 works, yielding an open 2-year mean citedness of 3.91 and an h-index of 144. In Crossref, the journal maintains 7,092 registered DOIs. Elsevier’s CiteScore uses a four-year calculation window, producing distinct numerical outputs from two-year ratios.

Responsible Assessment and DORA Guidance

Under the San Francisco Declaration on Research Assessment (DORA) and CoARA guidelines, institutions should avoid using journal-level metrics as proxies for individual article quality:

  • Skewed Citation Distributions: Within any journal, citation distribution is highly skewed; a minority of papers generates the majority of citations.
  • Discipline Differences: Applied process chemistry and chemical manufacturing have different citation practices than broad biology or multidisciplinary titles.
  • Direct Merit: Scale-up papers must be judged on experimental reproducibility, safety documentation, and mass balances rather than journal averages.

Related terms

Frequently Asked Questions

What is Organic Process Research & Development (OPRD)?

Organic Process Research & Development is an American Chemical Society journal focusing on chemical scale-up, pilot-plant operations, and industrial process safety.

How are two-year journal citation metrics calculated for OPRD?

Two-year metrics divide total citations received in a given year by the number of research articles and reviews published by OPRD across the two preceding years.

What open citation metrics are documented for OPRD?

OpenAlex records a 2-year mean citedness of 3.91, an h-index of 144, and over 165,000 total citations across 7,102 published works for OPRD.

Can OPRD’s journal metric be used to judge individual research papers?

No. Under DORA and CoARA guidelines, journal-level metrics evaluate aggregate publication performance and cannot substitute for evaluating an individual paper’s scientific rigor.

Sources

  • OpenAlex. Source Metadata for Organic Process Research & Development (Entity ID S107255770). URL: https://api.openalex.org/sources/s107255770. Date: 2026-11-08.
  • Crossref. Serial Record for Organic Process Research & Development (ISSN 1083-6160). URL: https://api.crossref.org/journals/1083-6160. Date: 2026-11-08.
  • National Library of Medicine. NLM Catalog Record for Organic Process Research & Development (NLM ID 9890443). URL: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=nlmcatalog&id=9890443. Date: 2026-11-08.

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