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v2026.1714 entries · CC-BY 4.0
Dictionary termTrack CStablev2026.2

Authentication of key resources

The verification, by methods appropriate to the resource type, of the identity and integrity of biological and chemical materials used in research, including cell lines, antibodies, animal models, and specialty chemicals.

ByCASRAI Editorial Board
· Last updated 21 May 2026

Examples

Worked examples

  • Is an instance

    A paper reporting STR-profile authentication of every cell line used, with RRID citation.

  • Is an instance

    An antibody validation appendix showing knockout-control reactivity testing.

Counter-examples

Looks similar, but isn't

  • Not an instance

    A mention of 'cells obtained from collaborator' with no authentication.

  • Not an instance

    A statement of catalogue number without functional verification.

Editorial commentary

Authentication is one pillar of the reproducibility-policy" class="text-primary underline-offset-2 hover:underline" data-autolinked="true" title="NIH Rigor and Reproducibility policy — CASRAI Dictionary">NIH Rigor and Reproducibility policy. For cell lines, STR profiling against the RRID database; for antibodies, validation against orthogonal reagents and registered RRIDs; for animal strains, genotype confirmation. RRIDs (Research Resource Identifiers) are persistent identifiers that make resource provenance machine-tractable.

References

  • NIH Notice NOT-OD-15-103; Bandrowski et al., 'The Resource Identification Initiative' (Journal of Comparative Neurology, 2015).

Also known as

resource authentication · cell-line authentication

Machine-readable encodings

Use in your systems

JATS XML <role> element
xml
<role vocab="credit"
      vocab-identifier="https://casrai.org/dictionary/"
      vocab-term="Authentication of key resources"
      vocab-term-identifier="https://casrai.org/dictionary/term/authentication-of-key-resources" />
Schema.org DefinedTerm (JSON-LD)
json
{
  "@context": "https://schema.org",
  "@type": "DefinedTerm",
  "name": "Authentication of key resources",
  "identifier": "https://casrai.org/dictionary/term/authentication-of-key-resources",
  "description": "The verification, by methods appropriate to the resource type, of the identity and integrity of biological and chemical materials used in research, including cell lines, antibodies, animal models, and specialty chemicals.",
  "inDefinedTermSet": "https://casrai.org/dictionary/domain/reproducibility-and-computational-research/",
  "url": "https://casrai.org/dictionary/term/authentication-of-key-resources",
  "sameAs": [
    "resource authentication",
    "cell-line authentication"
  ],
  "license": "https://creativecommons.org/licenses/by/4.0/"
}

Adopted by research universities worldwide

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