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v2026.1714 entries · CC-BY 4.0
Dictionary termTrack CStablev2026.2

Empirical reproducibility

The ability to obtain consistent observations when an empirical procedure (laboratory, field, or measurement) is independently repeated under matched conditions.

ByCASRAI Editorial Board
· Last updated 21 May 2026

Examples

Worked examples

  • Is an instance

    Two laboratories independently producing the same Western-blot band pattern from the same antibody lot.

  • Is an instance

    A field protocol producing comparable soil microbiome measurements across two seasons.

Counter-examples

Looks similar, but isn't

  • Not an instance

    Re-running the same statistical analysis on the same data file.

  • Not an instance

    A literature review.

Editorial commentary

Empirical reproducibility addresses the non-computational portion of research: instruments, reagents, sample preparation, environmental conditions, and human-factor variability. It is the principal concern of bench-science reproducibility initiatives such as the Reproducibility Project: Cancer Biology.

References

  • Goodman, Fanelli, Ioannidis (Science Translational Medicine, 2016); Errington et al., Reproducibility Project: Cancer Biology overview (eLife, 2021).

Also known as

wet-lab reproducibility · experimental reproducibility

Machine-readable encodings

Use in your systems

JATS XML <role> element
xml
<role vocab="credit"
      vocab-identifier="https://casrai.org/dictionary/"
      vocab-term="Empirical reproducibility"
      vocab-term-identifier="https://casrai.org/dictionary/term/empirical-reproducibility" />
Schema.org DefinedTerm (JSON-LD)
json
{
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  "@type": "DefinedTerm",
  "name": "Empirical reproducibility",
  "identifier": "https://casrai.org/dictionary/term/empirical-reproducibility",
  "description": "The ability to obtain consistent observations when an empirical procedure (laboratory, field, or measurement) is independently repeated under matched conditions.",
  "inDefinedTermSet": "https://casrai.org/dictionary/domain/reproducibility-and-computational-research/",
  "url": "https://casrai.org/dictionary/term/empirical-reproducibility",
  "sameAs": [
    "wet-lab reproducibility",
    "experimental reproducibility"
  ],
  "license": "https://creativecommons.org/licenses/by/4.0/"
}

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