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Cold sores: symptoms, treatment and how to avoid spreading them

Cold sores, also called fever blisters, are blisters on or around the lips, almost always caused by herpes simplex virus type 1. They go away on their own in 1 to 2 weeks, but they are contagious. An antiviral works best when started at the first tingle: the doctor assesses you by video and, if appropriate, prescribes.

Can we help by telehealth?YesWe can help by telehealth.
$79Doctor visit

Is it an emergency? Call 911.

Pay now, then choose your time right away. Full refund if you cancel 24 hours or more ahead.

See the cancellation policy

You can cancel for a full refund or change the time up to 24 hours before your visit. Within 24 hours you can't cancel and there's no refund. If you don't join in the first 10 minutes, there's no refund.

If you choose a time less than 24 hours away, it can't be cancelled or changed.

If the clinic can't see you, for example because of a technical problem on our side, we refund you in full.

Is this an emergency?

This is not an emergency service. Call 911 or go to the nearest emergency room if you have:

  • Blisters near the eyes: in-person care the same day
  • A newborn exposed to a cold sore who has blisters or seems unwell
  • A blistering rash spreading quickly in someone with eczema
  • Cold sores with a weakened immune system from illness or medicines

Warning signs: when to go to the ER

At a glance

Cold sores

Common symptoms

  • Itching, burning or tingling on the lips before blisters appear
  • Small fluid-filled blisters on or around the lips
  • Blisters that break open and crust over
  • With the first outbreak, sometimes a sore throat, fever and swollen glands
Other names
Fever blisters · Oral herpes · Herpes labialis
Treatment
Goes away on its own; a prescription antiviral when the medical evaluation calls for it, best at the first symptom
Possible complication
Herpes infection of the eye

What are cold sores?

Cold sores are also called fever blisters or oral herpes. According to MedlinePlus, they are almost always caused by herpes simplex virus type 1 (HSV-1), and most people in the U.S. have it by age 20. After the first infection, the virus stays dormant in the nerves of the face and can come back. In children, a first cold sore usually spreads through kisses or shared cups and utensils.

It spreads through direct contact with a sore or with the person (a kiss, for example) and by sharing utensils, towels or razors. It can spread even when no blisters are visible. It is not the same as canker sores, which are not contagious, or shingles, which is caused by a different virus.

How we treat cold sores by video

You see Dr. Diana Nieves Castro, a Puerto Rico–licensed general practice physician with several years of emergency-department experience, in English or Spanish. Cold sores are recognized by looking at them: with good light and the camera close, the doctor sees the blisters and asks when they started, how often you get them, and whether you have any condition that weakens your immune system.

If appropriate, the doctor prescribes an antiviral and we send your prescription to your pharmacy. If the sores are on the genitals, see STI testing and treatment or genital herpes. For other skin problems, see skin and acne care.

This is virtual urgent care for non-emergencies. We see adults and children of all ages; you need to be physically in Puerto Rico during the visit, and visitors are welcome.

Your doctor

Dr. Diana Nieves Castro, MD

General practice physician

Several years of emergency-department experience.

Founding Executive Director of The Health Initiative.

Meet the doctor

Your visit in 3 steps

Video doctor visits 24/7 — book online and choose your time right away.

  1. Request your visit.

    Book a visit and choose "Doctor visit". You pay by card when you request it. If you already take an antiviral and only need a refill, choose "Follow-up visit".

  2. See the doctor by video.

    We send you a secure video link. It works on your phone, tablet or computer.

  3. Get your plan.

    If appropriate, the doctor prescribes and we send your prescription to your pharmacy.

What a cold sore visit costs

A cold sore outbreak is handled in a doctor visit, the same price for every age, with no membership. A refill of a medicine you already take (non-controlled) is a follow-up visit. You pay by card when you request the visit, and you get a full refund if the clinic can’t see you. See all prices.

Cold sore symptoms

According to MedlinePlus, the most common symptoms are:

  • Itching, burning or tingling on the lips before blisters appear
  • Small fluid-filled blisters on or around the lips
  • Blisters that break open and crust over
  • With the first outbreak, sometimes a sore throat, fever and swollen glands

Cold sore treatment and triggers

Cold sores go away on their own in 1 to 2 weeks. Prescription antivirals work best when started at the first warning signs, the tingling or burning, before blisters form. According to MedlinePlus, over-the-counter creams help only a little. What does help: ice or a cold cloth, salt-water rinses, and acetaminophen or ibuprofen for pain, as the label directs.

Valacyclovir (Valtrex) and acyclovir for cold sores. These are prescription antivirals used for cold sores. According to MedlinePlus, valacyclovir is started as soon as symptoms appear, so it helps to book at the first tingle. If you have kidney disease or a kidney transplant, tell the doctor before she prescribes it. If you get outbreaks often, the doctor reviews with you whether suppressive therapy with valacyclovir is right for you. If appropriate, the doctor prescribes and we send your prescription to your pharmacy.

Outbreaks can be triggered by menstruation or hormone changes, fever, stress and the sun. Puerto Rico’s sun is strong all year: use a lip balm with sunscreen.

  • Don’t touch or pop the blisters, and wash your hands if you do touch them.
  • Don’t kiss or share utensils, glasses, towels or razors while you have blisters.
  • Avoid oral sex during an outbreak.
  • Don’t kiss newborn babies while you have a cold sore.

When to get in-person care or go to the ER

According to MedlinePlus, see a doctor if symptoms are severe or don’t go away after 2 weeks, or if your immune system is weakened by an illness or medicines.

Get in-person care the same day if you have blisters near your eyes, because herpes in the eye can cause scarring; if a newborn has been in contact with someone with a cold sore and develops blisters or seems unwell, because herpes in newborns can be serious; or if a person with eczema has a blistering rash that spreads quickly. For your safety, call 911 if a baby has a seizure, won’t feed or has trouble breathing.

Why a video visit

Why a video visit
ComparisonBy videoEmergency room
Getting thereFrom home: join from your phone, tablet or computer.Drive and find parking.
Hours and timeEvery day, any time (Puerto Rico time). Video doctor visits 24/7 — book online and choose your time right away.In Puerto Rico, a median of 4 h 52 min from arrival to departure for patients sent home (US: 2 h 42 min; Oct 2024–Sep 2025).1,2
Price$79 visit · $49 follow-up · $35 forms. You see it before you pay; no insurance needed.Depends on your insurance and on what is done.

For problems that are not emergencies. In an emergency, call 911.

How we care for you

  • We evaluate, diagnose and treat; if needed, we give you a lab order for a lab near you.

  • We see adults and children of all ages. Patients under 21: a parent with patria potestad (parental authority) or a legal guardian is on camera for the whole visit and shows photo ID.

  • Real-time video visit. We send you a secure video link. It works on your phone, tablet or computer.

  • If appropriate, the doctor prescribes and we send your prescription to your pharmacy.

  • You must be physically in Puerto Rico during the visit (visitors, tourists and cruise passengers are welcome).

  • In an emergency, call 911.

Frequently asked questions

How long do cold sores last?

They go away on their own in 1 to 2 weeks. If they are severe or don’t go away after 2 weeks, book a visit.

Are cold sores contagious?

Yes. They spread through direct contact, such as kissing, and by sharing utensils, glasses or towels. They can spread even without visible blisters, but the risk is higher while blisters are present.

When does treatment work best?

Antivirals work best when started at the first tingle or burning, before blisters form. That is why it helps to book as soon as you feel the warning signs.

Is valacyclovir used for cold sores?

Yes. According to MedlinePlus, valacyclovir (brand name Valtrex) is used for cold sores and is started as soon as symptoms appear. The doctor decides whether it is appropriate for you; tell her if you have kidney disease.

Can I kiss a baby if I have a cold sore?

No. Newborns can catch herpes from someone with a cold sore, and in them the infection can be serious. If you must care for a baby, wear a mask and wash your hands well.

Related topics

About this page

Author: The Health Initiative

Medical care provided by Dr. Diana Nieves Castro, MD (PR license 24027)

Disclosure: Founding Executive Director of The Health Initiative

Published: 2026-10-02 · Updated: 2026-10-11